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Bottles of water samples are set on a cart in June 2019.

Although it’s spotty and inconsistent in many places, wastewater testing is pointing to a new wave of COVID-19 infections, with as many as one-third of Americans expected to contract the disease by late February.

With pandemic fatigue also in full force, and deaths and hospitalizations well down from peaks in 2021 because of high vaccination and immunity rates, many people are inclined to shrug off the new wave, fueled by the JN.1 variant. But COVID-19 continues to take thousands of lives a month. Older, sicker people need to take particular precautions, experts point out, and everybody should think about the debilitating condition known as long COVID that can strike even young, healthy people and last years.